Device-measured vigorous intermittent lifestyle physical activity in daily bouts lasting up to 1 or up to 2 minutes, assessed with dominant-wrist accelerometers
VILPA
VILPA and Cancer Risk: UK Biobank Cohort Study
In 22,398 UK Biobank adults who did not exercise, brief device-measured bursts of vigorous daily activity were associated with lower rates of total and physical-activity-related cancer during about 6.7 years of follow-up.
Study overview
- Study title
- Vigorous Intermittent Lifestyle Physical Activity and Cancer Incidence Among Nonexercising Adults: The UK Biobank Accelerometry Study.
- Study authors
- Emmanuel Stamatakis, Matthew N Ahmadi, Christine M Friedenreich, Joanna M Blodgett, Annemarie Koster, Andreas Holtermann, Andrew Atkin, Vegar Rangul, Lauren B Sherar, Armando Teixeira-Pinto, Ulf Ekelund, I-Min Lee, Mark Hamer
- Population
- 22,398 self-reported nonexercising UK Biobank adults; mean age 62 years; 45.2% men and 54.8% women; 96.0% White
- Sample size
- 22398
- Duration
- Mean follow-up 6.7 years
- Comparator
- No VILPA
- Outcomes
- Total cancer incidence, Physical-activity-related cancer incidence
Intervention
Main findings
In this prospective cohort, daily VILPA was associated with lower incident total cancer and physical-activity-related cancer. The associations were near-linear, with stronger dose-response patterns for physical-activity-related cancer; findings were similar for bouts up to 1 and 2 minutes.
Limitations
Observational design cannot establish causality.